Cov Khoom Kawg
Tiv tauj peb
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![DOTA-E-[c(RGDfK)2]](https://img01.v15cdn.com/nopic.webp)
DOTA-E-[c(RGDfK)2] yog ib qho dimeric peptide uas muaj RGD sib lawv liag, siv los ua ib qho integrin ligand rau radiolabeling thiab positron emission tomography (PET) imaging. Nws yog siv nyob rau hauv vascular thiab qog kev tshawb fawb los kawm angiogenesis thiab integrin-txog cov txheej txheem.
Specifications
|
Sequence ib tsab ntawv code |
DOTA-E-[c(RGDfK)2] |
|
Sequence peb tsab ntawv code |
DOTA-Glu-[cyclo (Arg-Gly-Asp-d-Phe-Lys)] |
|
CAS Nr |
N/A |
|
Molecular Formula |
C75H113N23O23 |
|
Molecular Luj |
1704.88 |
|
Kev hloov kho |
Cyclization, DOTA |
|
Purity |
Peak Area los ntawm HPLC Ntau dua lossis sib npaug li 95% |
|
Daim ntawv |
Lyophilized |
|
Ntev Cia |
- 20 degree lossis qis dua |
| Rau kev tshawb fawb siv nkaus xwb. | |
Cov ntaub ntawv:
1. Lopez-Rodriguez, V., Gaspar-Carcamo, RE, Pedraza-Lopez, M., Rojas-Calderon, EL, Arteaga de Murphy, C., Ferro-Flores, G., & Avila-Rodriguez, MA (2015 ). Kev npaj thiab kev soj ntsuam ua ntej ntawm 66Ga-DOTA-E(c(RGDfK))₂ raws li qhov muaj peev xwm theranostic radiopharmaceutical. Nuclear Medicine thiab Biology, 42(2), 109-114.
2. Siitonen, R., Peuhu, E., Autio, A., Liljenbäck, H., Mattila, E., Metsälä, O., Käkelä, M., Saanijoki, T., Dijkgraaf, I., Jalkanen, S. ., Ivaska, J., & Roivainen, A. (2019). 68Ga-DOTA-E[c(RGDfK)]2 PET Imaging of SHARPIN-Regulated Integrin Activity nyob rau hauv nas. Phau ntawv Journal of Nuclear Medicine, 60(10), 1380–1387.
Cim npe nrov: dota-e-[c(rgdfk)2], dota-e-[c(rgdfk)2] xa khoom
Koj Tseem Yuav Zoo Li
