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Neurodegenerative Disease Research: Cov cuab yeej Peptide Advanced
Cov kab mob neurodegenerative xws li Alzheimer's (AD), Parkinson's (PD), thiab Huntington's (HD) yog qhov sib txuas nrog cov protein sib sau ua ke, suav nrog Amyloid-beta (A), Tau, thiab -synuclein.
Biorunstar muab siab -purity peptide synthesis kev daws teeb meem los txhawb cov kev tshawb fawb sib sau ua ke, kev txhim kho biomarker, thiab CNS tshuaj nrhiav pom.
Khoom Series: Peptide Portfolio rau Kev Tshawb Fawb Txog Kev Tshawb Fawb
Peb tshwj xeeb hauv kev sib txuas cov neuropeptides nyuaj, suav nrog kev sib sau ua ke - cov kab mob sib kis thiab cov hlab ntsha hlwb (BBB) shuttle peptides. Peb cov ntaub ntawv pov thawj suav nrog siab - cov khoom siv amyloid purity, kev tswj hwm peptides, thiab sau npe sojntsuam los txhawb kev tshawb nrhiav tshuaj CNS siab heev.
| Peptide khoom | Sequence / Qauv | Daim Ntawv Thov Kev Tshawb Fawb | |
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CAS: 107761-42-2 Nr. |
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA |
Cov khoom tseem ceeb ntawm amyloid plaques hauv AD; siab heev - muaj peev xwm sib sau ua ke. | |
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CAS: 131438-79-4 Nr. |
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV |
Feem ntau soluble A isoform; Nws yog ib qho tseem ceeb rau kev tshawb fawb txog fibrillation thiab vascular amyloid. | |
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CAS: 166090-74-0 Nr) |
DAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIA |
Feem ntau siv nyob rau hauv nas qauv ntawm Alzheimer tus kab mob; txawv ntawm tib neeg A los ntawm peb qhov kev hloov pauv ntawm txoj haujlwm 5, 10, thiab 13. |
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CAS: 144409-98-3 Nr. |
DAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVV |
Tus qauv isoform rau nas -raws li neurotoxicity thiab kev coj cwj pwm kev tshawb fawb. | |
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Amyloid- (42-1), Tib neeg (Rov qab) CAS: 317366-82-8 Nr. |
AIVVGGVMLGIIAGKNSGVDEAFFVLKQHHVEYGSDHRFEAD |
Kev tswj tsis zoo peptide los xyuas kom meej tias cov teebmeem lom lom yog ib ntus - tshwj xeeb. | |
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Amyloid- (40-1), Tib neeg (Rov qab) CAS: 144409-99-4 Nr. |
VVGGVMLGIIAGKNSGVDEAFFVLKQHHVEYGSDHRFEAD |
Kev tswj tsis zoo tau siv los ua kom muaj kev sib sau tshwj xeeb los ntawm tsis yog - cov teebmeem peptide tshwj xeeb. | |
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CAS: 131602-53-4 Nr. |
GSNKGAIIGLM | Qhov luv tshaj cytotoxic fragment ntawm A; siv rau kev tshuaj ntsuam neurotoxicity sai. | |
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Angiopep-2 |
TFFYGGSRGKRNNFKTEEY |
High-kev ua tau zoo ntshav-hlwb barrier (BBB) shuttle; lub hom phiaj LRP1 rau lub hlwb - phiaj xwm xa tshuaj. |
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| RVG 29 | YTIWMPENPRPGTPCDIFTNSRGKRASNG | Rabies Virus Glycoprotein fragment; neuron-kev taw qhia tshwj xeeb & ntshav-hlwb barrier (BBB) hla. | |
| p-Tau (Thr231) Core Fragment, Human (Phosphorylated) | ATPPK(pT)PPGSG | Epitope Mapping: Lub hom phiaj rau p-Thr231 cov tshuaj tiv thaiv tshwj xeeb. | |
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p-Tau (Thr231) Extended, Human, (Phosphorylated) |
KKVAVVR(pT)PPKSPSSAK | Extended fragment mimicking haiv neeg Tau ib puag ncig; optimized rau GSK-3 thiab PP2A enzymatic kev soj ntsuam | |
| -Synuclein (61-95) | EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFV | Core Aggregation Domain: Paub tias yog "Tsis yog-Amyloid Component" (NAC), thaj chaw hydrophobic no yog qhov tseem ceeb rau -synuclein fibrillization thiab insoluble Lewy lub cev tsim hauv Parkinson's Disease | |
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CAS: 33507-63-0 Nr. |
RPKPQQFFGLM-NH2 | Neuropeptide koom nrog hauv neuroinflamation thiab mob teeb liab txoj hauv kev. | |
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NPY, Human/Rat CAS: 82785-45-3 Nr. |
YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY-NH2 | Loj orexigenic neuropeptide modulating neuroprotective thiab kev ntxhov siab teb txoj hauv kev. | |
Customization & Zoo:Tshaj li Thr231, Biorunstar muaj cov kws tshaj lij synthesis rau qhov chaw Tau tseem ceeb (piv txwv li, p-Ser396, AT8 epitope, p-Ser199) thiab ntau yam kev hloov kho (FITC, CY3, CY5, CY7, Biotin, PEG, Azide). Tag nrho cov peptides raug txheeb xyuas los ntawm HPLC thiab MS kom ntseeg tau tias muaj purity siab thiab meej phosphorylation nyob.
Related Synthesis Cases & Nug
Peb tshwj xeeb hauv kev sib xyaw ua ke ntawm siab -hydrophobicity peptides (xws li, A 1-42) nrog kev tswj hwm monomeric thiab optimized solubility rau rhiab CNS kev soj ntsuam.
Case Studies:Saib qee yam ntawm peb cov kev sib txuas ua ke tsis ntev los no ntawmhttps://www.biorunstar.com/projects
Kev nug:sales@biorunstar.com