Cyclic peptide

 

Cyclic peptides

Cyclic peptides yog qhov ruaj khov dua li cov kab peptides vim lawv tsis kam mus rau proteases. Lawv tau txais kev txaus siab tseem ceeb los ntawm biotechnology thiab kev lag luam tshuaj.Biorunstar tuaj yeem tsim ntau hom cyclic peptides, raws li hauv qab no:

 

Peptides Head-rau-Tail Cyclization

Lub taub hau - mus rau -tail peptides tau yooj yim sib sau los ntawm kev tsim ntawm amide daim ntawv cog lus ntawm peptide tus kheej N-terminus amine thiab C-terminus carboxylic acid. Peb ua cov tshuaj tiv thaiv no nrog cov txiaj ntsig siab heev thiab niaj hnub muab cyclic peptides nrog ntau dua 98% purity.

Peptides Side Chain Cyclization

Biorunstar muaj lub peev xwm xaiv los tiv thaiv thiab tiv thaiv peptide sab chains, ua kom tsim cov lactam txuas ntawm lysine lossis diaminopropanoic acid thiab glutamic lossis aspartic acids. Peb tuaj yeem ua ntau qhov chaw sib txawv rau kev tsim choj.

Cys-Cys Disulfide Choj Cyclization

Disulfide- nplua nuj cyclic peptides tau ua rau muaj kev txaus siab rau kev txhim kho peptide-raws li kev kho mob vim lawv qhov tshwj xeeb ruaj khov rau tshuaj lom neeg, enzymatic, lossis thermal nres. Peb niaj hnub ua ke ib leeg, ob npaug thiab ntau qhov sib txuas ntawm cov disulfide ntawm peptides nrog siab purity yields.