Cov Khoom Kawg
Tiv tauj peb
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Exendin -3 yog ib qho tshuaj lom neeg peptide muab tau los ntawm cov venom ntawm Gila dab (Heloderma horridum). Nws belongs rau tsev neeg exendin ntawm peptides, uas muaj cov qauv zoo ib yam li glucagon-zoo li peptide-1 (GLP-1), thiab tau pom muaj txiaj ntsig tseem ceeb ntawm kev tso cov tshuaj insulin.
Specifications
|
Sequence ib tsab ntawv code |
HSDGTFTFTSDLSKQMEEEAVRLFIEWLKNGGPSSSGAPPPS-NH2 |
|
Sequence peb tsab ntawv code |
Nws-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp- Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 |
|
CAS Nr |
130357-25-4 |
|
Molecular Formula |
C184H282N50O61S1 |
|
Molecular Luj |
4202.63 |
|
Kev hloov kho |
C-terminal Amidation |
|
Purity |
Peak Area los ntawm HPLC Ntau dua lossis sib npaug li 95% |
|
Daim ntawv |
Lyophilized |
|
Ntev Cia |
- 20 degree lossis qis dua |
| Rau kev tshawb fawb siv nkaus xwb. | |
Cov ntaub ntawv:
1. Habener, JF, et al., "Gila Monster Venom, Gut Hormones, thiab Diabetes: Txoj Kev Cua Mus Rau Kev Tshawb Nrhiav Tshuaj," Pharmacy Times 2. Drucker, DJ, "Glucagon-zoo li peptide 1 thiab nws cov peev xwm kho tau," Cov txheej txheem ntawm National Academy of Sciences.
Cim npe nrov: exendin-3, exendin-3 cov chaw muag khoom
Koj Tseem Yuav Zoo Li
